Available here Image Courtesy:ġ.’D-Dimère’By Pocout – Own work, (CC BY-SA 3.0) via Commons WikimediaĢ.’Fibrinolysis’By Jfdwolff at en.wikipedia, (CC BY-SA 3.
Available hereĢ.“What Is the D-Dimer Test?” WebMD, WebMD. Reference:ġ.“Fibrin Degradation Products (FDP): What Is it?” Healthline, Healthline Media. This is the difference between D Dimer and FDP. Both these components are used as laboratory test specimens to analyze the risk of atherosclerosis. Plasmin is involved in the degradation process that will yield both FDP and D dimers. Fibrinolysis, or degradation of the fibrin network takes place as a post event for the clotting process. They are intermolecular covalent bonds.ĭ Dimer is the final product of fibrin degradation and is a type of FDP.įibrin Degradation Product or FDP is a product of fibrinolysis that remains after the clot has been dissolved.ĭ dimer and FDP are degradation products of fibrinolysis, whereas the most terminal dimeric end product is the D dimer. The dimeric structure of D dimer is held by isopeptide bonds between the gamma chains. D Dimer attains a dimeric structure as the name suggests. These chains are cross-linked with disulfide bonds. Thus, D dimer is composed of remnants of all three chains of fibrinogen that are termed as alpha, beta and gamma. Elevated D-dimer levels occur in situations of increased intravascular fibrin such as disseminated intravascular coagulation, surgery, burns, trauma, infection. It has a molecular weight of 180 kDa and is composed of extra linkages with D and E subunits of fibrin. It is the type of a Fibrin Degradation Product. Side by Side Comparison – D Dimer vs FDP in Tabular Formĭ Dimer is the final end product of fibrinolysis. A normal or negative test result usually indicates that a suspected person may not be suffering from any acute condition that is causing unnatural blood clot formation or breakdown. FDP do not contain extra linkages of D and E subunits of Fibrin, whereas D dimer is composed of extra linkages. In Conventional Units: 250 ng/mL D-dimer units (DDU) In SI Units: 0.50 mcg/mL fibrinogen equivalent units (FEU) Normal or Negative Test. The key difference between FDP and D Dimer is the structure. D Dimer is the final product of fibrin degradation and is a type of FDP.
Fibrin Degradation Product or FDP is a product of fibrinolysis that remains after the clot has been dissolved. These degradation products are known as Fibrin Degradation Products (FDPs). Fibrinolysis is the process where the fibrin is broken down by the action of plasmin. Fibrinogen is the protein in which the fibrin network is formed upon injury to tissue.
Fibrinogen is one of the main components involved in blood clotting process.